Check out this listing from the Zoo (no affiliation) for a masterbuilt Custom Shop "Tennessee Strat".

I've seen many Tele Deluxes with Strat necks/headstocks, and I've even seen Teles with Strat forearm and belly contours (which I happen to like).

But this may just be the first time I've seen an actual Tele pickguard/switch/bridge plate/bridge pickup on a Strat body (a string-through hardtail):



The transparent orange is definitely "unique", though not really my thing. Maybe a traditional Tele butterscotch would look more natural? Or that crimson red transparent finish they are putting on some of the Am Std Teles?

Replace that Strat neck pup with a humbucker, Keef style, and tune it to open G and that Strat would be raring to rip.