Red Lace Sensors are the hottest pickups Lace has ever produced. For an ACDC type of sound, my personal recommendations would be a pair of "Purple-Red" duallies in the neck and the bridge, the Eric Clapton Mid-Boost circuit, a Vox Clyde McCoy wah and an Ibanez Tube Screamer - all the necessary ingredients to become a naughty school boy like Angus himself!

Here's something to try if you want a nice, fat tone out of a stock S-S-S Strat:
-Switch in position 4 to blend the middle and bridge pups.
-Tone knob for middle pup all the way down to 2 or 1.

That usually works well for me.

EDIT: Well, that's interesting that the word filter was censoring the abbreviation for single-single-single as if I had just said that word spelled ess-hayche-eye-tee.

Angus plays an SG with humbuckers plugged into vintage Marshall tube amps like JTM45s and old 50w Master Volumes. In shows, he uses the 100w Marshall heads at 6 for the type of gain, but for solos, he uses the 50w heads on 10 for the gain, but lower power to match the volume.. Not sure about the effects he was actually using. The setup suggested on the above post sounds very close enough to my ears.

Below you'll find some useful tricks which help you to capture Angus' signature tone with all the necessary equipment and rock exactly like a serious naughty school boy has to do.

1. First things first, this article is written assuming that you already know how to play the guitar. If you don't, see some other articles about purchasing a guitar and then learn the chords: A, D, E, E5 (which is meaner than plain old E) and G. With these you can cover the main riffs of many of AC/DC's classics, such as "Highway to Hell", "Back in Black", and "TNT".

2. You don't need an expensive guitar to rock. But if you happen to be loaded, a Gibson SG '68 is the guitar that Angus Young plays. You can get these for around $1500-2500. If you can't afford an SG, try to find a guitar with humbucking pickups: Single-coils won't get you his sound. Vintage style ("PAF") humbuckers are ideal, so that's what you should look for. An ultra-modern pickup like EMG would be inappropriate when trying to copy Young's tone. Use your bridge pickup for most rhythm and lead playing. For a bluesier tone, use both pickups and turn down the tone knob to about 6 on the neck pickup.

3. You will also need an amp and a cable (except if you're serious, you want a transmitter and bookbag!) to connect the guitar to the amp. As I said above, Angus uses vintage Marshall tube amps like JTM45s and old 50w Master Volumes. In shows, he uses the 100w Marshall heads at 6 for the type of gain, but for solos, he uses the 50w heads on 10 for the gain, but lower power to match the volume.

4. Use the pick like Angus. One of the most identifying features about Angus Young's style is the way he uses his pick. Use an extra heavy gauge pick. Hold the pick so that about the width of a pencil is showing on the bottom, and strike the strings fairly violently, but don't let them buzz.

5. Copy Angus' vibrato. He has a really strong left hand, it takes some practice to nail it. Put emotion into it, not like Clapton but don't play it like metal. His solos are very bluesy. His vibrato is not a back and forth usually (B.B. king), more of an up and down.

6. Don't crank the distortion on your amp. Angus leaves almost every knob on his amp set at 5, except when he occasionally turns the mids up to 6! His sound is surprisingly clean and dynamic. The sound has to be clear, but mean. If you are using a Fender amp, make sure you crank up the mids to make it sound more like a Marshall. A tube amp will have a more touch-sensitive feel and will cover the fine line between clean and dirty more easily than a solid-state amp ever will. A Peavey Classic 30 (or something similar) is a good way to go if you are short on cash. Angus doesn't use any distortion or boost pedals (even during solos) so avoid them if you want a truly authentic tone. Use a mild overdrive pedal (instead of distortion) if you must use one at all!

7. Solo in Pentatonic and Hexatonic. He's a blues man!

- Before you start your solo at the beginning of "Thunderstruck" (or any other solo), raise your pick into the air as high as you can reach. Show off your weapon, the key that unlocks the vault of all great rock.

- During any guitar solo of Angus', you will notice him doing one of his signature dances. But his most popular by far is the one where he lifts his heels into the air, keeping his toes on the ground. (For all of you marching band people, this is just like marking time.) Start with either you left or right foot, but once you start, continue in this sequence: Left, Left, Right, Right, Left, Left, Right, Right...and so on. (This is going to be hard for marching band people, who have it drilled into their heads to go Left, Right, Left, Right...) Angus makes this dancing look easy but it is incredibly difficult to do so while playing guitar. The fact that he never misses a single note in live concerts while doing spectacular stage stunts is a testament to his immense skill.

8. Get the hair. It is not necessary to grow your hair, but it adds to the whole, rock 'n' roll feel. But if you do, be sure to swing your head around a lot and show off those gorgeous locks.

9. Movement. Also your going to obviously learn how to duck walk for those awesome solo's and don't forget to head bang, two with head up, two with head down (keep repeating this pattern). Another thing is to look your audience in the eye's and pull some great rockin' out faces. If you complete this through a whole song, if you did it right, you should be dripping with sweat.