Leave your guitar alone Hopkins and I, among others on the Forum, own the Gilmour guitar and can testify to the fact that just that won't do it.
In fact, with the SCN's on your Deluxe, and the S-1 system, you'll likely have more at your disposal with respect to a choice of tonal colors to choose from, than if you mucked it up.

The reason Gilmour went to the EMG's years back was because as the complexity of lighting technology they were using for their staging increased, so did the RF interference with the pickups in the Black Strat.
And since Fender, then a Phoenix rising from the ashes, invited him to sample two of their new '57RI Strats, the venture eventually gave rise to what we now call "The Red Strat" which he used for over twenty years, while the "Black Strat" went on loan to the Hard Rock Cafe.

There's a band called "Project Floyd" which performs at Five Towns College here on Long Island every summer, They do a consummate job, in the sense of what 'lomitus' had to say, with a stock Ernie Ball, and a Fender Stratocaster.

Doyle Bramhall II tells of learning that Roger Waters was planning on touring "The Wall." Bramhall owned a cassette recorder which would eliminate the lead guitar track on playback. So with that, he set about learning all the guitar parts for "The Wall" cold, auditioned, and got the gig. You can find some of that on YouTube. Have a listen to what the two guitarists on that tour put down. Bramhall playing left-handed on a reversed, upside-down, right handed Stratocaster, ala Albert King.

As an aside, if you want to hear a unique sound, listen to Arc Angels, and some of Bramhall's other work, such as "Welcome." Clapton and BB King do two Bramhall songs on "Riding With The King." You can recognize his musical form immediately.

There's been more than enough on this thread and who knows how many others in the past two years regarding chasing sound. To understand some of the impossibilities you should get a hold of as many Gilmour DVD's as you can and watch those hands, and how so much of that is generated by the use of a steel guitar, sliding, string bends in both directions, subtle use of trem, and changes in pickup selection. These, not to mention his new Peter Cornish floorboard, and the rest of the rack standing behind him.

Take particular note of Tim Renwick's following guitar solo, using nothing more than a stock Strat Plus, in "Another Brick in The Wall-Part 2 on the "Pulse DVD". Listening to the CD alone, you would think it were Gilmour, but no! Take note of the techniques, including the tapping with fingers and guitar pick.

So what we are saying here is that a capable musician, with the right feel, and the complementary gear, can find the tone from heaven. . Even yourself, in fact.

There's no arguing how BIG that sound is, and what one internalizes from it. So the emotional component which motivates you is understood by us all, otherwise we wouldn't be here as a group, sharing as we do.

Here's one from our history here which they left out

www.tonefromheaven.com

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ok guys lesson learned. i will leave my guitar alone,and get an EQ.
I will study Gilmours technique a little more to see if i can get that tone at least a little.Thanks for all the great input.
I would like a Strat that i could own that i could customize to my liking so any suggestions on that?