For a while I have been dissatisfied with some of the on board effects on my Spidervalve mkII 112 amp. I decided to put together my own pedalboard instead of using the Line 6 integrated Shortboard. The pedals I bought are:

Electro-Harmonix Memory Boy
Electro-Harmonix Micro Pog
Ibanez Tube Screamer TS9
Seymour Duncan pickup booster
Jim Dunlop Fuzz Face
TC Electronics Polytune
Ernie Ball Volume pedal

Here is a picture of the pedal chain as well as the shortboard above.



When I disconnect the Shortboard, there is a huge amount of background noise which cannot be filtered out. I've tried moving some of the pedals in the chain around but the noise persists. It's like a cycling wave of static. Even when all the pedals are inactive, this noise persists. Also when the pedals are activated, there is a serious drop in the output and sound quality of the amp as well as all of all of the pedals.

What is causing this noise? When I reconnect the Shortboard the noise goes away and all the pedals work perfectly so it cannot be an issue with the pedals. The shortboard connects to the amp by a cable like a network cable off a computer. I'm wondering if the amp only works with the shortboard but this sounds ridiculous and makes no sense. I've also dialled off all of the onboard effects on the amp but this makes no difference.

I'm thinking about doing a factory reset of the amp with the shortboard disconnected to see if this resolves the issue which is happening on all effects banks and patches. I don't want to do this until I have exhausted everything else.

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2012 Fender American Standard Stratocaster
2013 Fender Pure Vintage 65 Stratocaster
2003 Gibson ES-355
2015 Gibson Les Paul Traditional
2002 Gretsch Duo Jet
1980 Rickenbacker 360/12 Fireglo
2014 Martin 000X1AE
2014 Fender Blues Junior III

You may be experiencing a "ground loop". Try using a ground lift adapter (you know, the ol' 3-prong into 2 prong) on the plug that goes from the amp into the wall.
I'm not sure why you have the booster... seems to me, if you're using one, it should be first in line from the guitar. Boost the signal, then process it.
Also, are you running the chain into the guitar input on the amp? or an effects loop? I'm not familliar with the amp.
When I first got my Hot Rod Deluxe I was told I could use the "Pre Amp In" and "Power Amp Out" jacks as an effects loop. My amp kept cutting out on me. The forum straightened me out on that one. I now run the chain into the guitar input... and the order I have the pedals in makes a big difference as far as noise and performance.

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I tried using the power amp input at the back of the amp bypasses everything including basic amp functions like presence, bass, treble, middle etc..... which is not what I needed.

The pickup booster is just for my Strat to give the shrill bridge pickup a little extra.

I moved the volume pedal from the front of the chain to the back and strangely the whole thing now works. Makes no sense to me but I'm not going to mess with it now.

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2012 Fender American Standard Stratocaster
2013 Fender Pure Vintage 65 Stratocaster
2003 Gibson ES-355
2015 Gibson Les Paul Traditional
2002 Gretsch Duo Jet
1980 Rickenbacker 360/12 Fireglo
2014 Martin 000X1AE
2014 Fender Blues Junior III

That is strange. Some other methods for reducing noise would be to use quality patch cables and an isolated power supply for your pedals. The cabling is more important though. Guitarists blow so much money on gear but tend to forget how essential it is to preserve their signal with some proper cabling.